Appendix J. Current and Contingent EQ5D and VAS, additional analysis

Table 1. Adult respondents reporting the domain level for each FHS and for multiple FHS 

Domain	Level	% of respondents reporting: Food Allergy	% of respondents reporting: Coeliac Disease	% of respondents reporting: Food Intolerance	% of respondents reporting: Multiple	% of respondents reporting: Total
Mobility	1	69.34	77.36	60.55	52.33	66.62
Mobility	2	17.15	15.94	19.45	27.60	19.35
Mobility	3	7.66	4.13	13.42	12.54	8.84
Mobility	4	5.47	2.36	6.30	7.17	4.91
Mobility	5	0.36	0.20	0.27	0.36	0.28
Selfcare	1	85.04	94.88	78.08	77.06	85.20
Selfcare	2	5.47	3.15	13.15	13.62	8.20
Selfcare	3	7.66	1.57	6.85	8.24	5.40
Selfcare	4	1.09	0.39	1.92	1.08	1.05
Selfcare	5	0.73	0.00	0.00	0.00	0.14
Usual Activity	1	65.33	71.65	56.44	43.01	60.94
Usual Activity	2	17.15	19.29	23.84	29.03	21.95
Usual Activity	3	10.95	6.89	12.60	18.28	11.36
Usual Activity	4	4.01	2.17	6.85	8.96	5.05
Usual Activity	5	2.55	0.00	0.27	0.72	0.70
Pain	1	55.84	66.34	47.95	44.80	55.40
Pain	2	23.36	25.00	29.04	29.39	26.58
Pain	3	14.60	6.50	15.34	16.85	12.34
Pain	4	4.74	1.57	4.93	7.17	4.14
Pain	5	1.46	0.59	2.74	1.79	1.54
Anxiety	1	43.43	52.56	42.74	35.13	44.88
Anxiety	2	27.74	33.27	28.49	37.63	31.84
Anxiety	3	18.61	11.02	17.26	21.15	16.06
Anxiety	4	8.03	2.56	7.40	5.38	5.40
Anxiety	5	2.19	0.59	4.11	0.72	1.82

Table 2. Adult respondents reporting the domain level for the worst FHS or only FHS

Domain	Level	% of respondents reporting: Food Allergy	% of respondents reporting: Coeliac Disease	% of respondents reporting: Food Intolerance	% of respondents reporting: Multiple
Mobility	1	65.19	73.88	57.95	66.62
Mobility	2	20.00	17.97	20.68	19.35
Mobility	3	8.05	5.32	14.32	8.84
Mobility	4	6.49	2.50	6.82	4.91
Mobility	5	0.26	0.33	0.23	0.28
Selfcare	1	83.64	93.01	75.91	85.20
Selfcare	2	7.27	4.33	14.32	8.20
Selfcare	3	7.27	2.16	8.18	5.40
Selfcare	4	1.30	0.50	1.59	1.05
Selfcare	5	0.52	0.00	0.00	0.14
Usual Activity	1	60.52	67.22	52.73	60.94
Usual Activity	2	20.00	21.30	24.55	21.95
Usual Activity	3	12.47	8.99	13.64	11.36
Usual Activity	4	5.19	2.33	8.64	5.05
Usual Activity	5	1.82	0.17	0.45	0.70
Pain	1	53.25	63.06	46.82	55.40
Pain	2	25.71	26.62	27.27	26.58
Pain	3	14.55	7.82	16.59	12.34
Pain	4	4.68	2.00	6.59	4.14
Pain	5	1.82	0.50	2.73	1.54
Anxiety	1	40.26	50.42	41.36	44.88
Anxiety	2	31.43	34.11	29.09	31.84
Anxiety	3	19.22	12.48	18.18	16.06
Anxiety	4	7.53	2.50	7.50	5.40
Anxiety	5	1.56	0.50	3.86	1.82

Figure 1. Reported domain levels for the adult respondents compared with the UK population

Table 3. Reported domain levels for the adult respondents compared with the UK population

Domain	Level	Sample: Frequency	Sample: Percent	UK Population: Frequency	UK Population: Percent
Mobility	1	950	66.6	737	74.0
Mobility	2	276	19.4	113	11.3
Mobility	3	126	8.8	80	8.0
Mobility	4	70	4.9	58	5.8
Mobility	5	4	0.3	8	0.8
Selfcare	1	1215	85.2	861	92.1
Selfcare	2	117	8.2	39	4.2
Selfcare	3	77	5.4	26	2.8
Selfcare	4	15	1.1	7	0.7
Selfcare	5	2	0.1	2	0.2
Usual Activity	1	869	60.9	708	75.7
Usual Activity	2	313	21.9	122	13.0
Usual Activity	3	162	11.4	77	8.2
Usual Activity	4	72	5.0	22	2.4
Usual Activity	5	10	0.7	6	0.6
Pain	1	526	36.9	426	45.5
Pain	2	526	36.9	293	31.3
Pain	3	272	191.1	159	17.0
Pain	4	76	5.3	45	4.8
Pain	5	26	1.8	13	1.4
Anxiety	1	640	44.9	442	47.2
Anxiety	2	454	31.8	266	28.4
Anxiety	3	229	16.1	162	17.3
Anxiety	4	77	5.4	47	5.0
Anxiety	5	26	1.8	20	2.1

Source: UK population values taken from Feng, Y., Devlin, N., & Herdman, M. (2015). Assessing the health of the general population in England: how do the three- and five-level versions of EQ-5D compare?. Health and quality of life outcomes, 13, 171.

Figure 2. Scatter plot of calculated baseline and contingent health utility score from the EQ5D-5 L for adults

Footnote: Matrix of correlations 

Variables	(1) baseline health	(2) contingent health
(1) baseline health	1.000	-
(2) contingent health	0.889	1.000

Figure 3. Scatter plot of calculated baseline and contingent health utility score from the EQ-VAS for adults

Footnote: Matrix of correlations 

Variables	(1) baseline health	(2) contingent health
(1) baseline health	1.000	-
(2) contingent health	0.86	1.000

Table 4. Parent proxy values for children reporting the domain level for each FHS and for multiple FHS

Domain	Level	% of respondents reporting the level: Food Allergy	% of respondents reporting the level: Coeliac Disease	% of respondents reporting the level: Food Intolerance	% of respondents reporting the level: Multiple	Total
Mobility	1	90.88	67.86	91.30	75.71	86.99
Mobility	2	7.98	25.00	6.96	20.00	10.81
Mobility	3	1.14	7.14	1.74	4.29	2.20
Selfcare	1	85.19	71.43	84.35	71.43	82.09
Selfcare	2	13.39	25.00	13.04	24.29	15.71
Selfcare	3	1.42	3.57	2.61	4.29	2.20
Usual Activity	1	82.05	66.07	75.65	58.57	76.52
Usual Activity	2	14.81	26.79	20.00	34.29	19.26
Usual Activity	3	3.13	7.14	4.35	7.14	4.22
Pain	1	74.07	48.21	54.78	41.43	64.02
Pain	2	23.36	48.21	40.87	52.86	32.60
Pain	3	2.56	3.57	4.35	5.71	3.88
Anxiety	1	61.25	46.43	57.39	38.57	56.42
Anxiety	2	33.05	46.43	34.78	44.29	35.98
Anxiety	3	5.70	7.14	7.83	17.14	7.60

Table 5. Parent proxy values for children reporting the domain level for each FHS and for the worst FHS or only FHS

Domain	Level	% of respondents reporting the level: Food Allergy	% of respondents reporting the level: Coeliac Disease	% of respondents reporting the level: Food Intolerance	% of respondents reporting the level: Multiple
Mobility	1	90.00	70.15	86.40	86.99
Mobility	2	8.75	22.39	11.20	10.81
Mobility	3	1.25	7.46	2.40	2.20
Selfcare	1	83.75	71.64	82.40	82.09
Selfcare	2	14.00	26.87	15.20	15.71
Selfcare	3	2.25	1.49	2.40	2.20
Usual Activity	1	79.50	65.67	72.80	76.52
Usual Activity	2	17.25	26.87	21.60	19.26
Usual Activity	3	3.25	7.46	5.60	4.22
Pain	1	70.75	49.25	50.40	64.02
Pain	2	26.75	47.76	43.20	32.60
Pain	3	2.50	2.99	6.40	3.38
Anxiety	1	59.00	41.79	56.00	56.42
Anxiety	2	34.50	49.25	33.60	35.98
Anxiety	3	6.50	8.96	10.40	7.60

Figure 4. Reported domain levels for a child as valued by a parent compared with the UK population

Table 6. Reported domain levels for a child as valued by a parent compared with the UK population

Domain	Sample: Level	Sample: Frequency	Sample: Percent	UK Population: Frequency	UK Population: Percent
Mobility	1	950	66.6	950	86.99
Mobility	2	276	19.4	46	10.81
Mobility	3	126	8.8	9	2.20
Selfcare	1	1215	85.2	953	82.09
Selfcare	2	117	8.2	46	15.71
Selfcare	3	77	5.4	6	2.20
Usual Activity	1	869	60.9	916	76.52
Usual Activity	2	313	21.9	80	19.26
Usual Activity	3	162	11.5	9	4.22
Pain	1	526	36.9	865	64.02
Pain	2	526	36.9	131	32.60
Pain	3	272	19.1	9	3.38
Anxiety	1	640	44.9	660	56.42
Anxiety	2	454	31.8	322	35.98
Anxiety	3	229	16.1	23	7.60

Source: UK population values taken from EQ5D-Youth

Figure 5. Scatter plot of calculated baseline and contingent health utility score from the EQ5D-3L (proxy) 

Footnote: Matrix of correlations 

Variables	(1) baseline health	(2) contingent health
(1) baseline health	1.000	-
(2) contingent health	0.75	1.000

Figure 6. Scatter plot of calculated baseline and contingent health utility score from the EQ-VAS (proxy)

Footnote: Matrix of correlations 

Variables	(1) baseline health	(2) contingent health
(1) baseline health	1.000	-
(2) contingent health	0.68	1.000